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This study adds to a body of research showing the benefits of Pycnogenol . Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . . Pycnogenol can help control blood pressure, which helps improve overall heart health. But what makes this miracle ingredient so amazing? Work with your pediatrician to see if there are contraindications for each child. After taking a break for one to two weeks, they can start taking it again for several weeks. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? It may cause side effects such as: Risks. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. New research shows . In a study of 76 people with allergic asthma, Pycnogenol (100 mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. Erythritol: Is This Healthy Sweetener the Real Deal? Researchers suggest that it may have stronger benefits than elastic compression stockings. Pycnogenol lowered leukotrienes as well. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. (2006). In a good-quality study, 100 patients with osteoarthritis of the knee were treated for three months either with 150 mg of Pycnogenol a day or placebo. However, research on these two groups is limited [71, 15]. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. DIM and other plant indoles are found in . In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. Pycnogenol is the registered trademark name for a French formula. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Dizziness. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Pycnogenol is a compound of natural chemicals. In 1535, a French explorer by the name of Jacques Cartier found himself ice-bound on the St. Lawrence River. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. Most anal fissures heal with home treatment after a few days or weeks. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. For most people, pine bark extract doesnt cause any side effects. Information is shared for educational purposes only. Proper nutrition is essential for ADHD treatment. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. If you choose to use Pycnogenol, follow the dosage instructions on the label. A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. The Benefits of DIM. After stopping Pycnogenol for one month, symptoms Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. They were given Pycnogenolfor a period of 10 days. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. These benefits appeared to persist for some time even after stopping supplementation [72]. The specific tree from which the bark is extracted is called a maritime pine. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. Interactions. Research into Pycnogenol has revealed some promising results in over 30 health conditions. View as: Grid List. Pycnogenol seems to help with asthma and allergies. The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Consequently, blood pressure is lowered. Pycnogenol acts as a sustained-release formulation. You should also avoid using pine bark extract without talking to your doctor first if you: You should also do additional research or talk to your doctor before taking pine bark extract if you also take: While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. from the bark of the French maritime pine tree. All rights reserved. This supplement possibly activates the immune system. In one trial of 77 people with type 2 diabetes, pycnogenol (100 mg/day) for 12 weeks lowered both blood sugar levels and HbA1c, a marker of long-term blood glucose levels [31]. It also seems to help with cell regeneration and replication. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Pycnogenol also treatment improved blood vessel function. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. This ensures that there is a healthy flow of blood to and from the heart. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. Various studies, referenced at uofmhealth.org, have shown that a daily dosage of Pycnogenol . Another one of its exemplary effects is helping manage blood pressure levels. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. Add to Cart. No side effects were noted, unlike its synthetic counterpart. Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. Boost gastrointestinal health. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. Learn more about how to get even skin tone. ", Panminerva Medica: "Supplementation with Pycnogenol improves signs and symptoms of menopausal transition.". Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. Pine bark extract can make a great addition to your nutritional arsenal for its potent antioxidant support, as well as its added support for blood flow, blood sugar, inflammation, immunity, brain function and skin support. Here are 12 benefits of ginkgo biloba. One study involved a four-week treatment period followed by one week of no treatment or observation period. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Research indicates that Pycnogenol provides an increase in survival performance of train athletes. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. $31.99. Pycnogenol may reduce glucose levels, but it doesnt appear to increase insulin production or insulin sensitivity. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. Help your body fight the effects of normal aging. As a skin cream, its safe to use for about seven days. (5). Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Pycnogenol was featured on The Dr. Oz Show in January 2013, . Eliminate blood clots. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. This study adds to a body of research showing the benefits of Pycnogenol for improving circulation and blood flow, strengthening the vascular system and managing cholesterol. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. There are also several other natural ADHD remedies you can try. Additionally, athletes have endured less cramping and muscle pain when using the extract. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. Rating: 100%. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Dr. Drew explains the benefits of probiotics for the gut microbiome and talks about the rise of leaky gut, and Dr. Steve shares how emotional stress can have real physical effects on the heart. A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. Side effects. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. Pycnogenol led to a reduction of muscle cramps from 4.8 a week to 1.3 at week four. It is chronic venous insufficiency, a common disease among people who are obese or elderly and those who lead a sedentary lifestyle. Its quality is specified in the United States Pharmacopeia [3]. Discover what the research says about elimination diets, foods to eat, and more. There havent been any studies looking at long-term liver damage. but is for informational and educational purposes alone. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. Too much pressure signals that your heart might be working too hard. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. It does this by improving the time it takes the body to reach a fatigued state through increased serum NAD+ levels. COPD. 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin.